Alternative NamesAquaporin-4; AQP-4; WCH4; Mercurial-insensitive water channel; MIWC; AQP4;
Application(s)WB
Antibody HostRabbit
Antibody TypePolyclonal
SpecificityThe specificity of this antibody has been confirmed by WB against the antigen. Human; rat; predicted to react with mouse due to sequence homology;
Species ReactivityHuman, Mouse (Predicted), Rat
Immunogen DescriptionA synthetic peptide (FTIFASCDSKRTDVTGS) corresponding to a region (172-188) from human Aquaporin 4. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
ConjugateUnconjugated
Purity DescriptionAffinity purified on antigen column
Application DetailsWestern Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Human Aquaporin 4 (isoform 2) has a predicted length of 323 amino acids and MW of 35 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetAquaporin 4 (AQP4)
SpecificityThe specificity of this antibody has been confirmed by WB against the antigen. Human; rat; predicted to react with mouse due to sequence homology;
Target Host SpeciesHuman
Species ReactivityHuman, Mouse (Predicted), Rat
Antibody HostRabbit
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide (FTIFASCDSKRTDVTGS) corresponding to a region (172-188) from human Aquaporin 4. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
Purity DescriptionAffinity purified on antigen column
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
Storage InstructionsAt least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesAquaporin-4; AQP-4; WCH4; Mercurial-insensitive water channel; MIWC; AQP4;
Scientific BackgroundAquaporin 4 functions as a water-specific channel which regulates body water balance and mediates water flow within the central nervous system. Aquaporin 4 is a multi-pass membrane protein expressed predominantly in the brain as well as muscle, heart, kidney, lung and trachea.