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Connexin-26 (Cx26), Rabbit Polyclonal Antibody
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Catalog Number
R-1005
- Product Name Connexin-26 (Cx26), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Connexin-26 (Cx26) Polyclonal Antibody (Unconjugated), suitable for WB.
- Alternative Names GJB2; Cx26; Gap junction beta-2 protein;
- Application(s) WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; mouse; rat; rabbit;
- Species Reactivity Human, Mouse, Rabbit, Rat
- Immunogen Description A synthetic peptide (CYLFIRYCSGKSKRPV) corresponding to the amino acid sequence 211-226 from rat Connexin-26.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Connexin-26 (Cx26) Polyclonal Antibody (Unconjugated), suitable for WB.
- Application(s) WB
- Application Details Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. The predicted length of rat Connexin-26 is 226 residues and MW of 26 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Connexin-26 (Cx26)
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; mouse; rat; rabbit;
- Target Host Species Rat
- Species Reactivity Human, Mouse, Rabbit, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (CYLFIRYCSGKSKRPV) corresponding to the amino acid sequence 211-226 from rat Connexin-26.
- Purity Description Affinity purified on antigen column
- Format Liquid (0.5 mL). 50% glycerol, 0.9 mg NaCl and 0.2 mg Na2HPO4
- Reconstitution Instructions The liquid formulation should be diluted in PBS (pH 7.4)
- Storage Instructions After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names GJB2; Cx26; Gap junction beta-2 protein;
- Uniprot Number P21994
- Uniprot Number/Name P21994 (CXB2_RAT)
- Scientific Background A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighbouring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-26 belongs to the class 1 (beta) group of connexins. Mutations in Connexin-26 are associated with genetically derived hearing impairments, including autosomal recessive non syndromic deafness.
- Shipping Temperature 2-8°C (on cold packs)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
