Connexin-26 (Cx26), Rabbit Polyclonal Antibody

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Catalog Number
R-1005

    Product Info

  • Product Name Connexin-26 (Cx26), Rabbit Polyclonal Antibody
  • Product Description google Rabbit anti-Connexin-26 (Cx26) Polyclonal Antibody (Unconjugated), suitable for WB.
  • Alternative Names GJB2; Cx26; Gap junction beta-2 protein;
  • Application(s) WB
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; mouse; rat; rabbit;
  • Species Reactivity Human, Mouse, Rabbit, Rat
  • Immunogen Description A synthetic peptide (CYLFIRYCSGKSKRPV) corresponding to the amino acid sequence 211-226 from rat Connexin-26.
  • Conjugate Unconjugated
  • Purity Description Affinity purified on antigen column
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-Connexin-26 (Cx26) Polyclonal Antibody (Unconjugated), suitable for WB.
  • Application(s) WB
  • Application Details Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. The predicted length of rat Connexin-26 is 226 residues and MW of 26 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Connexin-26 (Cx26)
  • Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; mouse; rat; rabbit;
  • Target Host Species Rat
  • Species Reactivity Human, Mouse, Rabbit, Rat
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide (CYLFIRYCSGKSKRPV) corresponding to the amino acid sequence 211-226 from rat Connexin-26.
  • Purity Description Affinity purified on antigen column
  • Format Liquid (0.5 mL). 50% glycerol, 0.9 mg NaCl and 0.2 mg Na2HPO4
  • Reconstitution Instructions The liquid formulation should be diluted in PBS (pH 7.4)
  • Storage Instructions After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names GJB2; Cx26; Gap junction beta-2 protein;
  • Uniprot Number P21994
  • Uniprot Number/Name P21994 (CXB2_RAT)
  • Scientific Background A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighbouring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-26 belongs to the class 1 (beta) group of connexins. Mutations in Connexin-26 are associated with genetically derived hearing impairments, including autosomal recessive non syndromic deafness.
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Western blot of Connexin 26 antibody R-1005-100 at 1-2 µg/ml in rat liver sections. Secondary antibody HRP conjugated goat anti-rabbit IgG at 1:3000 dilution.

    Citations & References