C-C Chemokine Receptor type 5 (CCR5), Rabbit Polyclonal Antibody

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Catalog Number
R-1043

    Product Info

  • Product Name C-C Chemokine Receptor type 5 (CCR5), Rabbit Polyclonal Antibody
  • Product Description google Rabbit anti-C-C Chemokine Receptor type 5 (CCR5) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
  • Alternative Names C-C CKR-5; CC-CKR-5; CCR-5; CCR5; HIV-1 fusion coreceptor; CHEMR13; CD195;
  • Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; expected to react with rat and mouse due to sequence homology
  • Species Reactivity Human, Mouse (Predicted), Rat (Predicted)
  • Immunogen Description A synthetic peptide (PCQKINVKQIAARLLP) corresponding to a region (19-34) from the N-terminus of human C-C Chemokine Receptor type 5. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
  • Conjugate Unconjugated
  • Purity Description Affinity purified on antigen column
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-C-C Chemokine Receptor type 5 (CCR5) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
  • Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
  • Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. Human CCR5 has a predicted length of 352 residues and MW of 41 kDa. A concentration of 0.5-1 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target C-C Chemokine Receptor type 5 (CCR5)
  • Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; expected to react with rat and mouse due to sequence homology
  • Target Host Species Human
  • Species Reactivity Human, Mouse (Predicted), Rat (Predicted)
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide (PCQKINVKQIAARLLP) corresponding to a region (19-34) from the N-terminus of human C-C Chemokine Receptor type 5. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
  • Purity Description Affinity purified on antigen column
  • Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
  • Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names C-C CKR-5; CC-CKR-5; CCR-5; CCR5; HIV-1 fusion coreceptor; CHEMR13; CD195;
  • Uniprot Number P51681
  • Uniprot Number/Name P51681 (CCR5_HUMAN)
  • Scientific Background C-C Chemokine Receptor type 5 (CCR5) is a G-protein coupled receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES. CCR5 and its ligands may also play important roles in the control of granulocytic lineage proliferation or differentiation as well as pathogenesis of viruses such as HIV.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Immunohistochemical staining with Rabbit polyclonal antibody to human C-C Chemokine Receptor type 5 (R-1043-100) at 2 µg/mL in Human Rectal Cancer Tissue. Secondary biotin conjugated goat anti-rabbit IgG antibody at 10 µg/mL.

    Citations & References