C-C Chemokine Receptor type 7 (CCR7), Rabbit Polyclonal Antibody

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Catalog Number
R-1044

    Product Info

  • Product Name C-C Chemokine Receptor type 7 (CCR7), Rabbit Polyclonal Antibody
  • Product Description google Rabbit anti-C-C Chemokine Receptor type 7 (CCR7) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
  • Alternative Names C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; MIP-3 beta receptor;EBV-induced G-protein coupled receptor 1; EBI1; BLR2; CDw197; CD197;
  • Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat;
  • Species Reactivity Human, Mouse, Rat
  • Immunogen Description A synthetic peptide (FKDLGCLSQEQLRQWSS) corresponding to a region (341-357) from the C-terminus of human C-C Chemokine Receptor type 7. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
  • Conjugate Unconjugated
  • Purity Description Affinity purified on antigen column
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-C-C Chemokine Receptor type 7 (CCR7) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
  • Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
  • Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0-2.0 µg/mL is recommended for WB. Human CCR-7 (precursor) has a predicted length of 378 residues and MW of 43 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target C-C Chemokine Receptor type 7 (CCR7)
  • Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; mouse; rat;
  • Target Host Species Human
  • Species Reactivity Human, Mouse, Rat
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide (FKDLGCLSQEQLRQWSS) corresponding to a region (341-357) from the C-terminus of human C-C Chemokine Receptor type 7. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
  • Purity Description Affinity purified on antigen column
  • Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
  • Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names C-C chemokine receptor type 7; C-C CKR-7; CC-CKR-7; CCR-7; MIP-3 beta receptor;EBV-induced G-protein coupled receptor 1; EBI1; BLR2; CDw197; CD197;
  • Uniprot Number P32248
  • Uniprot Number/Name P32248 (CCR7_HUMAN)
  • Scientific Background C-C Chemokine Receptor type 7 (CCR-7) is a G-protein coupled receptor for the MIP-3-beta chemokine. CCR-7 expression has been found in various lymphoid tissues and activated B- and T-lymphocytes. CCR-7 is highly expressed in B-cells infected with Epstein-Barr virus (EBV) and T-cells infected with herpes virus 6 or 7.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Immunohistochemical staining with rabbit polyclonal antibody to human C-C Chemokine Receptor type 7 of paraffin-embedded human rectal cancer sections at 1-2 µg/ml. Secondary biotinylated goat anti-rabbit IgG antibody (10 µg/ml).

    Citations & References