Alternative NamesER-beta; Nuclear receptor subfamily 3 group A member 2; ESR2; ESTRB; NR3A2;
Application(s)WB
Antibody HostRabbit
Antibody TypePolyclonal
SpecificityThe specificity of this antibody has been confirmed by WB against the antigen. Human. The antibody is predicted to react with rat due to sequence homology.
Species ReactivityHuman, Rat (Predicted)
Immunogen DescriptionA synthetic peptide (HGSIYIPSSYVDSHHEYPAMTFYS) corresponding to a region (27-50) from human Estrogen Receptor beta. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
ConjugateUnconjugated
Purity DescriptionAffinity purified on antigen column
Application DetailsWestern Blotting (WB). A concentration of 0.5-1.0 µg/mL is recommended for WB. Human Estrogen Receptor beta (isoform Beta-1) has a predicted length of 530 residues and MW of 59 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetEstrogen Receptor beta (ER-beta)
SpecificityThe specificity of this antibody has been confirmed by WB against the antigen. Human. The antibody is predicted to react with rat due to sequence homology.
Target Host SpeciesHuman
Species ReactivityHuman, Rat (Predicted)
Antibody HostRabbit
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide (HGSIYIPSSYVDSHHEYPAMTFYS) corresponding to a region (27-50) from human Estrogen Receptor beta. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
Purity DescriptionAffinity purified on antigen column
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
Storage InstructionsAt least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability.Avoid freeze-thaw cycles
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesER-beta; Nuclear receptor subfamily 3 group A member 2; ESR2; ESTRB; NR3A2;
Scientific BackgroundEstrogen Receptor beta (ESR2) belongs to the nuclear hormone receptor family. ESR2 binds estrogens with high affinity, similar to Estrogen Receptor alpha (ESR1). At least 8 isoforms of ESR2 are produced by alternate splicing.