Histamine H3 receptor (HH3R), Rabbit Polyclonal Antibody

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Catalog Number
R-1063

    Product Info

  • Product Name Histamine H3 receptor (HH3R), Rabbit Polyclonal Antibody
  • Product Description google Rabbit anti-Histamine H3 receptor (HH3R) Polyclonal Antibody (Unconjugated), suitable for WB.
  • Alternative Names HH3R; G-protein coupled receptor 97; HRH3; GPCR97;
  • Application(s) WB
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; Rat; Predicted to react with mouse due to sequence homology.
  • Species Reactivity Human, Mouse (Predicted), Rat
  • Immunogen Description A synthetic peptide (CPQKLKIQPHSSLEHCWK) corresponding to a region (428-445) from the C-terminus of human Histamine H3 receptor. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
  • Conjugate Unconjugated
  • Purity Description Affinity purified on antigen column
  • Regulatory Status For research use only.

    Specifications

  • Product Description Rabbit anti-Histamine H3 receptor (HH3R) Polyclonal Antibody (Unconjugated), suitable for WB.
  • Application(s) WB
  • Application Details Western Blotting (WB). A concentration of 0.75 µg/mL is recommended for WB. Human Histamine H3 receptor (isoform 1) has a predicted length of 445 residues and MW of 49 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Histamine H3 receptor (HH3R)
  • Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human; Rat; Predicted to react with mouse due to sequence homology.
  • Target Host Species Human
  • Species Reactivity Human, Mouse (Predicted), Rat
  • Antibody Host Rabbit
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description A synthetic peptide (CPQKLKIQPHSSLEHCWK) corresponding to a region (428-445) from the C-terminus of human Histamine H3 receptor. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
  • Purity Description Affinity purified on antigen column
  • Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
  • Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names HH3R; G-protein coupled receptor 97; HRH3; GPCR97;
  • Uniprot Number Q9Y5N1
  • Uniprot Number/Name Q9Y5N1 (HRH3_HUMAN)
  • Scientific Background The Histamine H3 receptor is a multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family. This protein is primarily expressed in the CNS. At least 7 isoforms are produced by alternative splicing. Expression of these isoforms varies with isoform 3 and isoform 7 being highly expressed in the thalamus, caudate nucleus and cerebellum while isoforms 5 and 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

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