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SARS-CoV-2 envelope protein, Rabbit Polyclonal Antibody
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Catalog Number
R-1959
- Product Name SARS-CoV-2 envelope protein, Rabbit Polyclonal Antibody
- Product Description Rabbit anti-SARS-CoV-2 envelope protein Polyclonal Antibody (Unconjugated), suitable for ELISA.
- Alternative Names SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Envelope protein, E protein
- Application(s) ELISA
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity Predicted reactivity based on immunogen sequence: SARS-CoV Envelope proteins: (100%)
- Species Reactivity Virus
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Immunogen Description
Anti-SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody (R-1959-100) was raised against a peptide corresponding to 10 amino acids near the amino terminus of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope protein.
The immunogen is located within the first 50 amino acids of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope. - Conjugate Unconjugated
- Concentration 1 mg/mL
- Purity Description Affinity-purified via peptide column.
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-SARS-CoV-2 envelope protein Polyclonal Antibody (Unconjugated), suitable for ELISA.
- Application(s) ELISA
- Application Details SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody can be used for the detection of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope protein in ELISA. It will detect 20 ng of free peptide at 1 μg/mL.
- Target SARS-CoV-2 envelope protein
- Specificity Predicted reactivity based on immunogen sequence: SARS-CoV Envelope proteins: (100%)
- Target Host Species Virus
- Species Reactivity Virus
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
-
Immunogen Description
Anti-SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody (R-1959-100) was raised against a peptide corresponding to 10 amino acids near the amino terminus of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope protein.
The immunogen is located within the first 50 amino acids of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope. - Homology Predicted reactivity based on immunogen sequence: SARS-CoV Envelope proteins: (100%)
- Isoform Information SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope has one isoform (75aa).
- Purity Description Affinity-purified via peptide column.
- Format Liquid. SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody is supplied in PBS containing 0.02% sodium azide. Conc.1 mg/mL
- Concentration 1 mg/mL
- Reconstitution Instructions Spin vial briefly before opening.
- Storage Instructions SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody can be stored at 2-8°C for three months and -20 ° C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Envelope protein, E protein
- Uniprot Number P0DTC4
- Uniprot Number/Name P0DTC4 (VEMP_SARS2)
- NCBI Official Full Name envelope protein
- NCBI Official Symbol E
- NCBI Organism SARS-CoV-2
- Scientific Background Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019–20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Envelope protein is a small polypeptide that contains at least one α-helical transmembrane domain. It involves in several aspects of the virus's life cycle, such as assembly, budding, envelope formation, and pathogenesis. E protein has membrane permeabilizing activity, which provides a possible rationale to inhibit in vitro ion channel activity of some synthetic coronavirus E proteins, and also viral replication (3).
- Research Area Infectious Disease
- Shipping Temperature 2-8°C (on cold packs)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
Specifications
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General References
Gorbalenya. bioRxiv: 2020.
Hui et al. Int J Infect Dis. 2020;91:264-266.
Pervushin et al. PLoS Pathog. 2009; 5(7): e1000511.