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SARS-CoV spike protein, Rabbit Polyclonal Antibody
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Catalog Number
R-1945
- Product Name SARS-CoV spike protein, Rabbit Polyclonal Antibody
- Product Description Rabbit anti-SARS-CoV spike protein Polyclonal Antibody (Unconjugated), suitable for ELISA.
- Alternative Names SARS-CoV Spike antibody: E2, Spike glycoprotein, E2, S glycoprotein
- Application(s) ELISA
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 65%, homology 88%)
- Species Reactivity Virus
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Immunogen Description
Anti-SARS-CoV Spike antibody (R-1945-100) was raised against a peptide corresponding to 17 amino acids near the center of SARS-CoV Spike glycoprotein.
The immunogen is located within amino acids 550-600 of SARS-CoV Spike. - Conjugate Unconjugated
- Concentration 1 mg/mL
- Purity Description Affinity-purified via peptide column.
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-SARS-CoV spike protein Polyclonal Antibody (Unconjugated), suitable for ELISA.
- Application(s) ELISA
- Application Details SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 2 ng of free peptide at 1 μg/mL.
- Target SARS-CoV spike protein
- Specificity Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 65%, homology 88%)
- Target Host Species Virus
- Species Reactivity Virus
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
-
Immunogen Description
Anti-SARS-CoV Spike antibody (R-1945-100) was raised against a peptide corresponding to 17 amino acids near the center of SARS-CoV Spike glycoprotein.
The immunogen is located within amino acids 550-600 of SARS-CoV Spike. - Homology Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 65%, homology 88%)
- Isoform Information SARS-CoV Spike has one isoform (1255aa).
- Purity Description Affinity-purified via peptide column.
- Format Liquid. SARS-CoV Spike Antibody is supplied in PBS containing 0.02% sodium azide. Conc.1 mg/mL
- Concentration 1 mg/mL
- Reconstitution Instructions Spin vial briefly before opening.
- Storage Instructions SARS-CoV Spike antibody can be stored at 2-8°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names SARS-CoV Spike antibody: E2, Spike glycoprotein, E2, S glycoprotein
- Uniprot Number P59594
- Uniprot Number/Name P59594 (SPIKE_SARS)
- NCBI Official Full Name Spike glycoprotein
- NCBI Official Symbol S
- NCBI Organism SARS coronavirus
- Scientific Background SARS Spike Antibody: A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.
- Research Area Infectious Disease
- Shipping Temperature 2-8°C (on cold packs)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
Specifications
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General References
Marra et al. Science 2003;300:1399-404.
Rota et al. Science 2003;300:1394-9.
Navas-Nartin et al. J Neurovirol. 2004;10:75-85.
Li et al. Nature 2003;426:450-4.