Brain-derived neurotrophic factor (BDNF), Chicken Polyclonal Antibody

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Catalog Number
C-1517

    Product Info

  • Product Name Brain-derived neurotrophic factor (BDNF), Chicken Polyclonal Antibody
  • Product Description google Chicken anti-Brain-derived neurotrophic factor (BDNF) Polyclonal Antibody (Unconjugated), suitable for ELISA.
  • Alternative Names Brain-derived neurotrophic factor; Abrineurin; proBDNF;
  • Application(s) ELISA
  • Antibody Host Chicken
  • Antibody Type Polyclonal
  • Specificity Mammalian BDNF
  • Species Reactivity Human, Mouse
  • Immunogen Description Mixture of two human BDNF peptides (73-87 and 194-208 aa). Both peptides are highly conserved in human and mouse.
  • Conjugate Unconjugated
  • Purity Description IgY
  • Regulatory Status For research use only.

    Specifications

  • Product Description Chicken anti-Brain-derived neurotrophic factor (BDNF) Polyclonal Antibody (Unconjugated), suitable for ELISA.
  • Application(s) ELISA
  • Application Details ELISA. Suggested dilution at 1:500 to 1:2,000. Biosensis recommends that the optimal working dilution should be determined by the end user.
  • Target Brain-derived neurotrophic factor (BDNF)
  • Specificity Mammalian BDNF
  • Target Host Species Human
  • Species Reactivity Human, Mouse
  • Antibody Host Chicken
  • Antibody Type Polyclonal
  • Antibody Isotype IgY
  • Conjugate Unconjugated
  • Immunogen Description Mixture of two human BDNF peptides (73-87 and 194-208 aa). Both peptides are highly conserved in human and mouse.
  • Purity Description IgY
  • Format Liquid. PBS with 0.02% Sodium Azide
  • Storage Instructions Short term storage at 2-8°C for one week. At -20°C as an undiluted liquid for up to 12 months.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Brain-derived neurotrophic factor; Abrineurin; proBDNF;
  • Uniprot Number P23560
  • Uniprot Number/Name P23560 (BDNF_HUMAN)
  • Scientific Background BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.