GDNF family receptor alpha-4 (GFR alpha-4), Chicken Polyclonal Antibody

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Catalog Number
C-1662

    Product Info

  • Product Name GDNF family receptor alpha-4 (GFR alpha-4), Chicken Polyclonal Antibody
  • Product Description google Chicken anti-GDNF family receptor alpha-4 (GFR alpha-4) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen.
  • Alternative Names GDNF receptor alpha-4; Persephin receptor; GDNFR-alpha-4; GFR-alpha-4;
  • Application(s) IHC-Frozen, WB
  • Antibody Host Chicken
  • Antibody Type Polyclonal
  • Specificity Human GFRa-4. This antibody does not cross-react with hGFRa-1, hGFRa-2, hGFRa-3
  • Species Reactivity Human
  • Immunogen Description Recombinant His-tagged human GFRa-4 protein produced using CHO-based cell line. For production of hGFRa-4, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.
  • Conjugate Unconjugated
  • Purity Description Affinity purified
  • Regulatory Status For research use only.

    Specifications

  • Product Description Chicken anti-GDNF family receptor alpha-4 (GFR alpha-4) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen.
  • Related Products GDNF family receptor alpha-1 (GFR alpha-1), Chicken Polyclonal Antibody
    GDNF family receptor alpha-2 (GFR alpha-2), Chicken Polyclonal Antibody
    GDNF family receptor alpha-3 (GFR alpha-3), Chicken Polyclonal Antibody
  • Application(s) IHC-Frozen, WB
  • Application Details WB, IHC. A dilution of 1:5 000-1:10 000 is recommended for Western blots and 1:1 000 to 1:3 000 for immunocytochemistry. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target GDNF family receptor alpha-4 (GFR alpha-4)
  • Specificity Human GFRa-4. This antibody does not cross-react with hGFRa-1, hGFRa-2, hGFRa-3
  • Target Host Species Human
  • Species Reactivity Human
  • Antibody Host Chicken
  • Antibody Type Polyclonal
  • Antibody Isotype IgY
  • Conjugate Unconjugated
  • Immunogen Description Recombinant His-tagged human GFRa-4 protein produced using CHO-based cell line. For production of hGFRa-4, glycosylphosphatidyl-inositol GPI-anchor was removed and protein was secreted to the cell culture supernatant. Protein was purified by Ni-affinity chromatography following gel-filtration from cell culture supernatant.
  • Sequence Uniprot Q9GZZ7
  • Purity Description Affinity purified
  • Format Liquid in PBS pH 7.4 containing no preservatives
  • Reconstitution Instructions ready to dilute once thawed
  • Storage Instructions Store at -80°C upon receipt. Divide antibody into aliquots upon receipt. Avoid multiple freeze-thaw cycles as product degradation may result.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names GDNF receptor alpha-4; Persephin receptor; GDNFR-alpha-4; GFR-alpha-4;
  • Uniprot Number Q9GZZ7
  • Uniprot Number/Name Q9GZZ7 (GFRA4_HUMAN)
  • Scientific Background GFR_-4 belongs to the GDNF receptor family. It is a glycosyl-phosphatidylinositol (GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor.
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Western-Blot detection of human GFRα-4, using Chicken polyclonal antibody to human GFRα-4. GFRα-4 was expressed by CHO cell culture. 100 ng of purified protein was loaded per lane. Line 1. hGFRα-4. Primary antibody dilution 1:5000 was used. Line 2. Prestained protein ladder (Naxo 8003).

    Citations & References