Short transient receptor potential channel 5 (TrpC5), Mouse Polyclonal Antibody

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Catalog Number
M-916

    Product Info

  • Product Name Short transient receptor potential channel 5 (TrpC5), Mouse Polyclonal Antibody
  • Product Description google Mouse anti-Short transient receptor potential channel 5 (TrpC5) Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Alternative Names Short transient receptor potential channel 5; Htrp-5; Htrp5; TRPC5; TRP5
  • Application(s) ELISA, WB
  • Antibody Host Mouse
  • Antibody Type Polyclonal
  • Specificity Specificity has been confirmed by ELISA against the antigen. Human. Other species have not been tested.
  • Species Reactivity Human
  • Immunogen Description Partial recombinant human TrpC5 [534-603] with a GST tag.
  • Conjugate Unconjugated
  • Purity Description Purified
  • Regulatory Status For research use only.

    Specifications

  • Product Description Mouse anti-Short transient receptor potential channel 5 (TrpC5) Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Application(s) ELISA, WB
  • Application Details This antibody is recommended for WB and ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Short transient receptor potential channel 5 (TrpC5)
  • Specificity Specificity has been confirmed by ELISA against the antigen. Human. Other species have not been tested.
  • Target Host Species Human
  • Species Reactivity Human
  • Antibody Host Mouse
  • Antibody Type Polyclonal
  • Antibody Isotype IgG
  • Conjugate Unconjugated
  • Immunogen Description Partial recombinant human TrpC5 [534-603] with a GST tag.
  • Purity Description Purified
  • Format Liquid. Storage buffer: 50% glycerol
  • Storage Instructions Keep aliquots stored at -20°C for higher stability. Avoid repetitive freeze/thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Short transient receptor potential channel 5; Htrp-5; Htrp5; TRPC5; TRP5
  • Uniprot Number Q9UL62
  • Uniprot Number/Name Q9UL62 (TRPC5_HUMAN)
  • Scientific Background
    It has been demonstrated that TrpC1 and TrpC5 are subunits of a heteromeric neuronal channel in mammalian brain. TrpC5 is thought to form a receptor-activatd non-selective permeant cation channel. It is probably operated by a phosphatidylinositol second messenger system activated by receptor kinases or G-protein coupled receptors. It has also been shown to be calcium-selective and it may be also activated by intracellular calcium store depletion. TrpC5 protein was shown to be present in hippocampal neuronal growth cones, neuronal cell bodies, areas consistent with new synapse formation, and cytoplasmic transport vesicles along neuronal processes. TrpC5 is expressed in brain with higher levels in fetal brain. Influxes of calcium via voltage-gated channels play a role in neuronal outgrowth and it was suggested that TrpC5 is a candidate for the regulation of calcium waves.
  • Shipping Temperature 2-8°C (on cold packs)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

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    Citations & References