Dihydropyrimidinase-related protein 3 (DRP-3), Mouse Monoclonal Antibody

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Catalog Number
M-826

    Product Info

  • Product Name Dihydropyrimidinase-related protein 3 (DRP-3), Mouse Monoclonal Antibody
  • Product Description google Mouse anti-Dihydropyrimidinase-related protein 3 (DRP-3) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Alternative Names Dihydropyrimidinase-related protein 3; unc-33-like phoshoprotein; ULIP protein; collapsin response mediator protein 4; CRMP-4; DPSYL3; CRMP4; DRP3; ULIP
  • Application(s) ELISA, WB
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Specificity The specificity of this antibody has been shown by WB and ELISA against the GST tagged recombinant DRP-3 protein. This antibody cross reacts with mouse and rat DRP-3 protein.
  • Species Reactivity Human, Mouse, Rat
  • Immunogen Description Partial recombinant protein of human DRP-3 (amino acids 457 to 556) with a GST tag.
  • Conjugate Unconjugated
  • Purity Description Protein G purified immunoglobulin
  • Regulatory Status For research use only.

    Specifications

  • Product Description Mouse anti-Dihydropyrimidinase-related protein 3 (DRP-3) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
  • Application(s) ELISA, WB
  • Application Details This antibody is recommended for WB and direct ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Dihydropyrimidinase-related protein 3 (DRP-3)
  • Specificity The specificity of this antibody has been shown by WB and ELISA against the GST tagged recombinant DRP-3 protein. This antibody cross reacts with mouse and rat DRP-3 protein.
  • Target Host Species Human
  • Species Reactivity Human, Mouse, Rat
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Antibody Isotype IgG
  • Clone Name 1B8
  • Conjugate Unconjugated
  • Immunogen Description Partial recombinant protein of human DRP-3 (amino acids 457 to 556) with a GST tag.
  • Purity Description Protein G purified immunoglobulin
  • Format Lyophilized from PBS pH 7.2
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
  • Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Dihydropyrimidinase-related protein 3; unc-33-like phoshoprotein; ULIP protein; collapsin response mediator protein 4; CRMP-4; DPSYL3; CRMP4; DRP3; ULIP
  • Uniprot Number Q14195
  • Uniprot Number/Name Q14195 (DPYL3_HUMAN)
  • Scientific Background
    DRP-3 belongs to the hydantoinase/dihydropyrimidase subfamily. It is required for signalling by class 3 semaphorins and remodelling of the cytoskeleton. It also plays a role in axon guidance, neuronal growth cone collapse and cell migration. It exists as a homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL4 or DPYSL5. The unprocessed precursor is 570 amino acids long and has an estimated molecular weight of 61.9 kDa. It is mainly expressed in heart and skeletal muscle but is also strongly expressed in fetal brain and spinal cord. It localises to the cytoplasm and growth cone. This protein interacts with synaptic vesicle protein 2 and SH3A domain of intersectin.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Western blot analysis on Jurkat cell lysate using Mouse monoclonal antibody to human DRP-3, catalogue number M-826-100. The major band detected has a molecular weight of ~64.8 kDa.

    Citations & References