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Brain-specific homeobox/POU domain protein 3C (Brn-3C), Mouse Monoclonal Antibody
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Catalog Number
M-859
- Product Name Brain-specific homeobox/POU domain protein 3C (Brn-3C), Mouse Monoclonal Antibody
- Product Description Mouse anti-Brain-specific homeobox/POU domain protein 3C (Brn-3C) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names POU domain class 4 transcription factor 3; Brain-specific homeobox/POU domain protein 3C; POU4F3; BRN3C
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Species Reactivity Human
- Immunogen Description Partial recombinant human Brn-3C (100-191) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Brain-specific homeobox/POU domain protein 3C (Brn-3C) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB, immunofluorescence and sandwich ELISA. The recommended dilution for this antibody is 10 µg/mL for IHC. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Brain-specific homeobox/POU domain protein 3C (Brn-3C)
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 5B8
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human Brn-3C (100-191) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names POU domain class 4 transcription factor 3; Brain-specific homeobox/POU domain protein 3C; POU4F3; BRN3C
- Uniprot Number Q15319
- Uniprot Number/Name Q15319 (PO4F3_HUMAN)
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Scientific Background
Brn-3C may play a role in determining or maintaining the identities of a small subset of visual system neurons. It is expressed in the brain and it seems to be specific to the retina. Defects in Brn-3C are the cause of non-syndromic sensorineural deafness autosomal dominant type 15 (DFNA15) which is a form of sensorineural hearing loss. Sensorineuraldeafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
