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Neuroblast differentiation-associated protein AHNAK, Mouse Monoclonal Antibody
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Catalog Number
M-824
- Product Name Neuroblast differentiation-associated protein AHNAK, Mouse Monoclonal Antibody
- Product Description Mouse anti-Neuroblast differentiation-associated protein AHNAK Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Desmoyokin; AHNAK
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody was demonstrated by WB against the recombinant protein. Because of is large size, full length detection in westerns is often difficult. Most reports focus on much smaller partial fragments however published reports using polyclonals do show full length AHANK is detectable. Most commonly 20-42 kDa N terminal fragments are detected and resolved on most gels.
- Species Reactivity Human
- Immunogen Description Partial recombinant human AHNAK protein (1-101) with a GST tag. It is reported that the monoclonal epitope is the N-terminal part of AHNAK1.
- Conjugate Unconjugated
- Purity Description IgG purified monoclonal antibody.
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Neuroblast differentiation-associated protein AHNAK Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for use in WB , direct ELISA and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Neuroblast differentiation-associated protein AHNAK
- Specificity The specificity of this antibody was demonstrated by WB against the recombinant protein. Because of is large size, full length detection in westerns is often difficult. Most reports focus on much smaller partial fragments however published reports using polyclonals do show full length AHANK is detectable. Most commonly 20-42 kDa N terminal fragments are detected and resolved on most gels.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 3G7
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human AHNAK protein (1-101) with a GST tag. It is reported that the monoclonal epitope is the N-terminal part of AHNAK1.
- Purity Description IgG purified monoclonal antibody.
- Format Lyophilized from PBS pH 7.2, 150mM NaCl.
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Desmoyokin; AHNAK
- Uniprot Number A1A586
- Uniprot Number/Name Q09666 (AHNK_HUMAN)
- Scientific Background Neuroblast differentiation-associated protein or AHNAK and known as desmoyokin, is a large protein (molecular mass, 700 kD) phosphoprotein that can be found as a nuclear protein, a structural scaffold protein and a plasma membrane protein. It was originally identified first as a nuclear phosphoprotein, then later as scaffold protein bovine and named desmoyokin due to its localization pattern in the desmosomal plaque. AHNAK has been shown to be essential for pseudopod protrusion and cell migration but may also play key roles in blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
