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Achaete-scute homolog 1 (ASH-1), Mouse Monoclonal Antibody
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Catalog Number
M-803
- Product Name Achaete-scute homolog 1 (ASH-1), Mouse Monoclonal Antibody
- Product Description Mouse anti-Achaete-scute homolog 1 (ASH-1) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Achaete-scute homolog 1; HASH1; ASCL1; ASH1; MASH1
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody was confirmed by WB and ELISA against the recombinant protein with the GST tag. GST tag alone was used as a negative control. Human, other species have not been tested.
- Species Reactivity Human
- Immunogen Description The antigen was a partial recombinant protein of human ASCL1 (amino acids 137 to 236) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Achaete-scute homolog 1 (ASH-1) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB, ELISA and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Achaete-scute homolog 1 (ASH-1)
- Specificity The specificity of this antibody was confirmed by WB and ELISA against the recombinant protein with the GST tag. GST tag alone was used as a negative control. Human, other species have not been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG2a, kappa
- Clone Name 3D3
- Conjugate Unconjugated
- Immunogen Description The antigen was a partial recombinant protein of human ASCL1 (amino acids 137 to 236) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2, 150mM NaCl.
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Achaete-scute homolog 1; HASH1; ASCL1; ASH1; MASH1
- Uniprot Number P50553
- Uniprot Number/Name P50553 (ASCL1_HUMAN)
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Scientific Background
This protein plays a role in neuronal commitment and differentiantion in most regions of the CNS and of several neuronal lineages in the PNS. It is also essential for the generation of olfactory and autonomic neurons. The unprocessed precursor is 236 amino acids in length and 25.45KDa. ASCL1 contains one basic helix-loop-helix (bHLH) domain. It activates transcription by binding to the Ebox (5'-CANNTG-3') and efficient DNA binding requires dimerisation with other bHLH proteins. It forms a heterodimer with TCF3.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
