Paired box protein Pax-5, Mouse Monoclonal Antibody

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Catalog Number
M-857

    Product Info

  • Product Name Paired box protein Pax-5, Mouse Monoclonal Antibody
  • Product Description google Mouse anti-Paired box protein Pax-5 Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, ELISA.
  • Alternative Names B-cell-specific transcription factor; BSAP; PAX5
  • Application(s) ELISA, IHC-Frozen, WB
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
  • Species Reactivity Human
  • Immunogen Description Partial recombinant human Paired box protein Pax-5 (192-302) with a GST tag.
  • Conjugate Unconjugated
  • Purity Description Protein G purified immunoglobulin
  • Regulatory Status For research use only.

    Specifications

  • Product Description Mouse anti-Paired box protein Pax-5 Monoclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, ELISA.
  • Application(s) ELISA, IHC-Frozen, WB
  • Application Details This antibody is recommended for WB, IHC and sandwich ELISA. The recommended dilution for this antibody is 1 µg/mL for IHC. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Paired box protein Pax-5
  • Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
  • Target Host Species Human
  • Species Reactivity Human
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Antibody Isotype IgG
  • Clone Name 8F9
  • Conjugate Unconjugated
  • Immunogen Description Partial recombinant human Paired box protein Pax-5 (192-302) with a GST tag.
  • Purity Description Protein G purified immunoglobulin
  • Format Lyophilized from PBS pH 7.2
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
  • Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names B-cell-specific transcription factor; BSAP; PAX5
  • Uniprot Number Q02548
  • Uniprot Number/Name Q02548 (PAX5_HUMAN)
  • Scientific Background
    Paired box protein Pax-5 is a member of the paired box (PAX) family of transcription factors. This family has a highly conserved DNA-binding motif known as the paired box. Paired box protein Pax-5 may play an important role in B-cell differentiation as well as neural development and spermatogenesis. It is involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. It localises to the nucleus and is expressed at early B-cell differentiation in the developing CNA and in adult testis. A defect in Paired box protein Pax-5 is a cause of acute lymphoblastic leukemia.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Immunohistochemical detection of Paired box protein Pax-5 on formalin fixed, paraffin-embedded, human tonsil tissue. Anti-Paired box protein Pax-5 primary antibody, catalogue number M-857-100, was used at a concentration of 1 µg/mL.

  • Western blot detection of GST tagged recombinant Paired box protein Pax-5.

    Citations & References