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Beta-1,3-acetylglucosaminyltransferase radical fringe, Mouse Monoclonal Antibody
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Catalog Number
M-861
- Product Name Beta-1,3-acetylglucosaminyltransferase radical fringe, Mouse Monoclonal Antibody
- Product Description Mouse anti-Beta-1,3-acetylglucosaminyltransferase radical fringe Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Beta-1;3-N-acetylglucosaminyltransferase radical fringe; O-fucosylpeptide-3-beta-N-acetylglucosaminyltransferase; RFNG
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Species Reactivity Human
- Immunogen Description Partial recombinant human Radical fringe homolog (amino acids 222-330) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Beta-1,3-acetylglucosaminyltransferase radical fringe Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB, immunofluorescence and direct ELISA. The recommended dilution for this antibody is 10 µg/mL for immunofluorescence. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Beta-1,3-acetylglucosaminyltransferase radical fringe
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 6C7
- Conjugate Unconjugated
- Immunogen Description Partial recombinant human Radical fringe homolog (amino acids 222-330) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.2
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Beta-1;3-N-acetylglucosaminyltransferase radical fringe; O-fucosylpeptide-3-beta-N-acetylglucosaminyltransferase; RFNG
- Uniprot Number Q9Y644
- Uniprot Number/Name Q9Y644 (RFNG_HUMAN)
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Scientific Background
The Drosophila melanogaster 'fringe' gene is a secreted signaling protein that is involved in the formation of boundaries between groups of cells during development. It acts by modulating the activation of te Notch signal transduction pathway. A human radical fringe homolog was identified in 1997. There is evidence to show that radical fringe homolog may be involve in limb formation and in neurogenesis in humans. It is a glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. It is a single-pass type II membrane protein which localises to the golgi apparatus membrane. It belongs to the glycosyltransferase 31 family.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
