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SMAD4, Mouse Monoclonal Antibody
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Catalog Number
M-992
- Product Name SMAD4, Mouse Monoclonal Antibody
- Product Description Mouse anti-SMAD4 Monoclonal Antibody (Unconjugated), suitable for WB.
- Alternative Names Smad4; DPC4; co-Smad
- Application(s) WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human
- Species Reactivity Human
- Immunogen Description Recombinant full length human Smad4 (DPC4)
- Conjugate Unconjugated
- Purity Description IgG
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-SMAD4 Monoclonal Antibody (Unconjugated), suitable for WB.
- Application(s) WB
- Application Details Western Blotting (WB). A concentration of 2.0-4.0 µg/mL is recommended for WB. Human Smad4 has a predicted length of 552 residues and a MW of 60 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target SMAD4
- Specificity The specificity of this antibody has been confirmed by WB against the antigen. Human
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name IMD-89
- Conjugate Unconjugated
- Immunogen Description Recombinant full length human Smad4 (DPC4)
- Purity Description IgG
- Format Lyophilized from 1.2% sodium acetate, 2 mg BSA, 0.01 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS (pH 7.4) to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Smad4; DPC4; co-Smad
- Uniprot Number Q13485
- Uniprot Number/Name Q13485 (SMAD4_HUMAN)
- Scientific Background Smad proteins are important components of signal transduction by the TGF-beta superfamily from the cell surface into the nucleus. Once in the nucleus, Smad proteins target a number of DNA binding proteins to stimulate transcription. Smad4, also known as the common-mediator Smad (co-Smad), interacts with the receptor-regulated Smad proteins (R-SMAD). The R-SMAD class includes Smad2 and Smad3.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.