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Melanoma growth stimulatory activity (MGSA), Mouse Monoclonal Antibody
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Catalog Number
M-820
- Product Name Melanoma growth stimulatory activity (MGSA), Mouse Monoclonal Antibody
- Product Description Mouse anti-Melanoma growth stimulatory activity (MGSA) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Melanoma growth stimulatory activity; growth-regulated alpha protein; GRO-alpha(1-73); C-X-X motif chemokine 1; neutrophil-activating protein 3; NAP-3; CXCL1
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity The specificity of this antibody has been confirmed by WB and ELISA against the GST tagged recombinant human MSGA protein. Human. Other species have not been tested.
- Species Reactivity Human
- Immunogen Description Partial recombinant protein of human MGSA (amino acids 36 to 107) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Melanoma growth stimulatory activity (MGSA) Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Melanoma growth stimulatory activity (MGSA)
- Specificity The specificity of this antibody has been confirmed by WB and ELISA against the GST tagged recombinant human MSGA protein. Human. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 7A11
- Conjugate Unconjugated
- Immunogen Description Partial recombinant protein of human MGSA (amino acids 36 to 107) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.4
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Melanoma growth stimulatory activity; growth-regulated alpha protein; GRO-alpha(1-73); C-X-X motif chemokine 1; neutrophil-activating protein 3; NAP-3; CXCL1
- Uniprot Number P09341
- Uniprot Number/Name P09341 (GROA_HUMAN)
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Scientific Background
MGSA belongs to the intercrine alpha (chemokine CXC) familly. In this family, the first two of the four conserved residues are separated by a single amino acid. MGSA has chemotactic activity for neutrophils and may play a role in inflammation. MGSA is secreted and subsequently proteolytically processed at the N-terminus by peripheral blood monocytes to form GRO-alpha(4-73), GRO-alpah(5-73) and GRO-alpha(6-73). In vitro, these processed forms show a 30 fold increase in chemotactic activity. The unprocessed precursor has a length of 107 amino acids and a predicted molecular weight of 11.3KDa.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
