Protein S-100 beta, Mouse Monoclonal Antibody

As low as US$427.00
Only %1 left
Catalog Number
M-1746

    Product Info

  • Product Name Protein S-100 beta, Mouse Monoclonal Antibody
  • Product Description google Mouse anti-Protein S-100 beta Monoclonal Antibody (Unconjugated), suitable for IHC-Frozen, IHC-Paraffin-embedded.
  • Alternative Names S100B; Calcium binding protein B1;
  • Application(s) IHC-Frozen, IHC-Paraffin-embedded
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Specificity The specificity of this antibody has been confirmed by IHC against the antigen. Human, rabbit and rat. May cross-react with horse and monkey S100-beta based on amino acid sequence similarities.
  • Species Reactivity Bovine, Horse (Predicted), Human, Primate (Predicted), Rabbit, Rat
  • Immunogen Description Bovine brain S-100b
  • Conjugate Unconjugated
  • Purity Description Ascites
  • Regulatory Status For research use only.

    Specifications

  • Product Description Mouse anti-Protein S-100 beta Monoclonal Antibody (Unconjugated), suitable for IHC-Frozen, IHC-Paraffin-embedded.
  • Application(s) IHC-Frozen, IHC-Paraffin-embedded
  • Application Details Immunohistochemistry (IHC). A concentration of 1.0-2.0 µg/mL is recommended to detect S100 beta subunit in paraffin embedded tissues. Antigen retrieval by heat is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Protein S-100 beta
  • Specificity The specificity of this antibody has been confirmed by IHC against the antigen. Human, rabbit and rat. May cross-react with horse and monkey S100-beta based on amino acid sequence similarities.
  • Target Host Species Bovine
  • Species Reactivity Bovine, Horse (Predicted), Human, Primate (Predicted), Rabbit, Rat
  • Antibody Host Mouse
  • Antibody Type Monoclonal
  • Antibody Isotype IgG
  • Clone Name SH-B1
  • Conjugate Unconjugated
  • Immunogen Description Bovine brain S-100b
  • Purity Description Ascites
  • Format Lyophilized from mouse ascites fluid containing 1.2% sodium acetate, 2 mg BSA, with 0.01 mg NaN3 as preservative.
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 1 mL of sterile-filtered PBS buffer to achieve an antibody concentration of 100 µg/mL. Centrifuge to remove any insoluble material.
  • Storage Instructions 12 months after purchase at -20°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names S100B; Calcium binding protein B1;
  • Uniprot Number P02638
  • Uniprot Number/Name P02638 (S100B_BOVIN)
  • Scientific Background Protein S100 beta belongs to the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Among brain cells, S100 beta is often used as a marker for astrocytes. The 2 subunits of S100 protein are the products of separate genes. The beta subunit is present in all S100 positive cells and tumours whereas the alpha subunit is detectable only in specific tissues such as heart, skeletal muscle and brain. The S100 protein is a homodimer composed of two alpha subunits (S100a) or two beta subunits (S100b) or as a heterodimer with one alpha and beta subunit (S100ab or S100ao). This antibody reacts specifically with the beta subunit.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

    Images, Protocols & SDS

    Citations & References