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Transcription factor HES-1, Mouse Monoclonal Antibody
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Catalog Number
M-841
- Product Name Transcription factor HES-1, Mouse Monoclonal Antibody
- Product Description Mouse anti-Transcription factor HES-1 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Hairy and enhancer of split 1; Hairy-like; HHL; Hairy homolog; HES1; HL; HRY
- Application(s) ELISA, WB
- Antibody Host Mouse
- Antibody Type Monoclonal
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Species Reactivity Human
- Immunogen Description Partial recombinant protein of human Transcription factor HES-1 (aa 36 to 143) with a GST tag.
- Conjugate Unconjugated
- Purity Description Protein G purified immunoglobulin
- Regulatory Status For research use only.
Product Info
- Product Description Mouse anti-Transcription factor HES-1 Monoclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details This antibody is recommended for WB, and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Transcription factor HES-1
- Specificity Specificity has been confirmed by WB and direct ELISA against the antigen. Human. Other species have not been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Mouse
- Antibody Type Monoclonal
- Antibody Isotype IgG
- Clone Name 4D9
- Conjugate Unconjugated
- Immunogen Description Partial recombinant protein of human Transcription factor HES-1 (aa 36 to 143) with a GST tag.
- Purity Description Protein G purified immunoglobulin
- Format Lyophilized from PBS pH 7.3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for higher stability or at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Hairy and enhancer of split 1; Hairy-like; HHL; Hairy homolog; HES1; HL; HRY
- Uniprot Number Q14469
- Uniprot Number/Name Q14469 (HES1_HUMAN)
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Scientific Background
Transcription factor HES-1 is a transcriptional repressor of genes that require a basic helix-loop-helix protein for their transcription. It needs to form a complex with a corepressor protein (Groucho) to repress transcription. Transcription factor HES-1 has a particular type of basic domain which contains a helix-interrupting proline, that binds to the N-box (CACNAG) rather than the canonical E-box (CANNTG). It also consists of a C-terminal WRPW motif that is necessary for the interaction with Groucho. It localises to the nucleus.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
