1800 605-5127
+61 (0)8 8352 7711
Suppressor of cytokine signaling 1 (SOCS-1), Rabbit Polyclonal Antibody
As low as
US$427.00
Only %1 left
Catalog Number
R-1029
- Product Name Suppressor of cytokine signaling 1 (SOCS-1), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Suppressor of cytokine signaling 1 (SOCS-1) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names Janus kinase binding protein; STAT induced STAT inhibitor 1; SOCS-1; JAK-binding protein; JAB; SSI-1; TIP-3; Tec-interacting protein 3; SSI1; TIP3;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; rat; predicted to react with mouse due to sequence homology;
- Species Reactivity Human, Mouse (Predicted), Rat
- Immunogen Description A synthetic peptide (NPVLRDYLSSFPFQI) corresponding to a region (197-211) from the C-terminus of human SOCS1.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Suppressor of cytokine signaling 1 (SOCS-1) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. Human SOCS1 has a predicted length of 211 residues and MW of 24 kDa. A concentration of 0.5-1.0 µg/mL is recommended to detect SOCS1 in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Suppressor of cytokine signaling 1 (SOCS-1)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; rat; predicted to react with mouse due to sequence homology;
- Target Host Species Human
- Species Reactivity Human, Mouse (Predicted), Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (NPVLRDYLSSFPFQI) corresponding to a region (197-211) from the C-terminus of human SOCS1.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Janus kinase binding protein; STAT induced STAT inhibitor 1; SOCS-1; JAK-binding protein; JAB; SSI-1; TIP-3; Tec-interacting protein 3; SSI1; TIP3;
- Uniprot Number O15524
- Uniprot Number/Name O15524 (SOCS1_HUMAN)
- Scientific Background The SOCS (Suppressor of cytokine signaling) family of proteins has at least 8 members; SOCS1 to SOCS7 and CIS (cytokine inducible SH2 containing protein). SOCS1 has a role in the negative regulation of cytokines that signal through the JAK/STAT3 pathway.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
