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Basic Fibroblast growth factor (Basic FGF), Sheep Polyclonal Antibody

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Catalog Number
S-008
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    Product Info

  • Product Name Basic Fibroblast growth factor (Basic FGF), Sheep Polyclonal Antibody
  • Product Description google Sheep anti-Basic Fibroblast growth factor (Basic FGF) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen.
  • Alternative Names Heparin-binding growth factor 2; HBGF-2; Basic fibroblast growth factor; bFGF; Prostatropin; FGF2; FGFB
  • Application(s) IHC-Frozen, WB
  • Antibody Host Sheep
  • Antibody Type Polyclonal
  • Specificity A high level of specificity for bFGF was shown by immunohistochemistry for this antiserum. This antibody is known to react with human, mouse and rat basic FGF.
  • Species Reactivity Human, Mouse, Rat
  • Immunogen Description Recombinant human basic FGF
  • Conjugate Unconjugated
  • Purity Description Whole serum
  • Regulatory Status For research use only.

    Specifications

  • Product Description Sheep anti-Basic Fibroblast growth factor (Basic FGF) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen.
  • Application(s) IHC-Frozen, WB
  • Application Details IHC (frozen), WB. Recommended to be used at a dilution of 1: 1000 to 1:2000 for both applications. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
  • Target Basic Fibroblast growth factor (Basic FGF)
  • Specificity A high level of specificity for bFGF was shown by immunohistochemistry for this antiserum. This antibody is known to react with human, mouse and rat basic FGF.
  • Target Host Species Human
  • Species Reactivity Human, Mouse, Rat
  • Antibody Host Sheep
  • Antibody Type Polyclonal
  • Antibody Isotype Mixed
  • Conjugate Unconjugated
  • Immunogen Description Recombinant human basic FGF
  • Purity Description Whole serum
  • Format Lyophilized
  • Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
  • Storage Instructions After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Heparin-binding growth factor 2; HBGF-2; Basic fibroblast growth factor; bFGF; Prostatropin; FGF2; FGFB
  • Uniprot Number P09038
  • Uniprot Number/Name P09038 (FGF2_HUMAN)
  • Scientific Background Fibroblast growth factors (FGFs), a heparin binding growth factor, exhibit widespread mitogenic and neurotrophic activities in a variety of different cells including mesenchymal, neuroectodermal and endothelial cells. aFGF (FGF-1) and bFGF (FGF-2) are present in relatively high levels in CNS. aFGF is expressed by a subset of neuronal populations, while bFGF is expressed by astrocytes, both lack signal peptides. Human bFGF is a 17.2 kDa protein containing 155 amino acid residues. FUNCTION: The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. SUBUNIT: Monomer. Interacts with CSPG4 and FGFBP1. Found in a complex with FGFBP1, FGF1 and FGF2. MISCELLANEOUS: This protein binds heparin more strongly than does aFGF. SIMILARITY: Belongs to the heparin-binding growth factors family.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 41116161
  • Regulatory Status For research use only.

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