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Epidermal growth factor receptor (EGFR)-Fc Chimera, Purified Recombinant Protein
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Catalog Number
PE-1240
- Product Name Epidermal growth factor receptor (EGFR)-Fc Chimera, Purified Recombinant Protein
- Product Description Epidermal growth factor receptor (EGFR)-Fc Chimera, Purified Recombinant Protein, suitable to Block.
- Alternative Names Receptor tyrosine-protein kinase erbB-1; EGFR; Urogastrone; Pro-epidermal growth factor; EGF R; c-erbB-1; ERBB1;
- Application(s) Block
- Purity Description >95%, as determined by SDS-PAGE and visualized by Coomassie Brilliant Blue
- Purity % > 95%
- Regulatory Status For research use only.
Product Info
- Product Description Epidermal growth factor receptor (EGFR)-Fc Chimera, Purified Recombinant Protein, suitable to Block.
- Application(s) Block
- Target Epidermal growth factor receptor (EGFR)
- Target Host Species Human
- Antigen Produced In HEK293
- Sequence A DNA sequence encoding the signal peptide and extracellular domain of human Epidermal Growth Factor Receptor (amino acids 1-525) was fused to the Fc region of human IgG1 (amino acids 90-330). The chimeric protein was expressed in modified human 293 cells.
- Purity Description >95%, as determined by SDS-PAGE and visualized by Coomassie Brilliant Blue
- Purity % > 95%
- Format The EGF receptor-Fc chimera consists of 5-30% carbohydrate by weight. When reconstituted in 0.5 mL sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.
- Reconstitution Instructions It is recommended that 0.5 mL of sterile phosphate-buffered saline be added to the vial.
- Storage Instructions Lyophilized products should be stored at 2 to 8°C. Following reconstitution short-term storage at 2-8°C is recommended, with longer-term storage in aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Receptor tyrosine-protein kinase erbB-1; EGFR; Urogastrone; Pro-epidermal growth factor; EGF R; c-erbB-1; ERBB1;
- Uniprot Number P00533
- Uniprot Number/Name P00533 (EGFR_HUMAN)
- Scientific Background Epidermal Growth Factor (EGF) Receptor binds to EGF and other members of the EGF family such as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. At least 4 isoforms are produced by alternative splicing (reference SWISSPROT). The EGF receptor is a single-pass type I membrane protein containing an extracellular receptor domain, a transmembrane region and an intracellular domain with tyrosine kinase function.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 12352202
- Regulatory Status For research use only.