L-selectin-Fc Chimera, Human, Purified Recombinant Protein

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Catalog Number
PE-1247

    Product Info

  • Product Name L-selectin-Fc Chimera, Human, Purified Recombinant Protein
  • Product Description google L-selectin-Fc Chimera, Human, Purified Recombinant Protein, suitable to Block.
  • Alternative Names Lymph node homing receptor; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; TQ1; gp90-MEL; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; CD62L; SELL; LNHR; LYAM1;
  • Application(s) Block
  • Purity Description >95%, as determined by SDS-PAGE and visualized by silver stain
  • Purity % > 95%
  • Regulatory Status For research use only.

    Specifications

  • Product Description L-selectin-Fc Chimera, Human, Purified Recombinant Protein, suitable to Block.
  • Application(s) Block
  • Target L-selectin
  • Target Host Species Human
  • Antigen Produced In HEK293
  • Sequence A DNA sequence encoding the signal peptide, pro-peptide and extracellular domain of human L-Selectin (amino acids 1-343) was fused to the Fc region of human IgG1 (amino acids 93-330). The chimeric protein was expressed in modified human 293 cells.
  • Purity Description >95%, as determined by SDS-PAGE and visualized by silver stain
  • Purity % > 95%
  • Format The L-Selectin-Fc chimera consists of 20-45% carbohydrate by weight. When reconstituted in 0.5 mL sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.
  • Reconstitution Instructions Reconstitute with sterile-filtered phosphate-buffered saline to a concentration of 100 µg/mL.
  • Storage Instructions Lyophilized products should be stored at 2 to 8°C. Following reconstitution, short-term storage at 2-8°C is recommended and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.
  • Batch Number Please see item label.
  • Expiration Date 12 months after date of receipt (unopened vial).
  • Alternative Names Lymph node homing receptor; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; TQ1; gp90-MEL; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; CD62L; SELL; LNHR; LYAM1;
  • Uniprot Number P14151
  • Uniprot Number/Name P14151 (LYAM1_HUMAN)
  • Scientific Background L-selection (CD26L) is a cell surface adhesion protein constitutively expressed on all classes of human leukocytes. The L-Selectin glycoprotein is composed of a C-type lectin family domain at the amino terminus, an EGF-like domain, two short consensus repeat (SCR) sequences, a transmembrane domain and a short cytoplasmic tail. L-Selectin contains 7 potential N- linked glycosylation sites.
  • Shipping Temperature 25°C (ambient)
  • UNSPSC CODE 12352202
  • Regulatory Status For research use only.

    Images, Protocols & SDS

  • Gel analysis of L-selectin-Fc Chimera.

    Lane 1: MW marker
    Lane 2: L-selectin-Fc Chimera (10 µg)
    Lane 3: L-selectin-Fc Chimera (10 µg) treated with PNGase F to remove potential N-linked glycans

    Citations & References