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Stem cell factor receptor (SCFR)-Fc Chimera, Human, Purified Recombinant Protein
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Catalog Number
PE-1244
- Product Name Stem cell factor receptor (SCFR)-Fc Chimera, Human, Purified Recombinant Protein
- Product Description Stem cell factor receptor (SCFR)-Fc Chimera, Human, Purified Recombinant Protein, suitable to Block.
- Alternative Names Mast/stem cell growth factor receptor; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117
- Application(s) Block
- Purity Description >95%, as determined by SDS-PAGE and visualized by silver stain
- Purity % > 95%
- Regulatory Status For research use only.
Product Info
- Product Description Stem cell factor receptor (SCFR)-Fc Chimera, Human, Purified Recombinant Protein, suitable to Block.
- Application(s) Block
- Target Stem cell factor receptor (SCFR)
- Target Host Species Human
- Antigen Produced In HEK293
- Sequence A DNA sequence encoding the signal peptide and extracellular domain of human Stem Cell Factor Receptor (amino acids 1-520) was fused to the Fc region of human IgG1 (amino acids 93-330). The chimeric protein was expressed in modified human 293 cells.
- Purity Description >95%, as determined by SDS-PAGE and visualized by silver stain
- Purity % > 95%
- Format The SCFR-Fc Chimera consists of 5-45% carbohydrate by weight. When reconstituted in 0.5 mL sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.
- Reconstitution Instructions It is recommended that 0.5 mL of sterile phosphate-buffered saline be added to the vial.
- Storage Instructions Lyophilized products should be stored at 2 to 8°C. Following reconstitution short-term storage at 2-8°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Mast/stem cell growth factor receptor; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117
- Uniprot Number P10721
- Uniprot Number/Name P10721 (KIT_HUMAN)
- Scientific Background Stem Cell Factor Receptor (SCFR) is a member of the receptor tyrosine kinase family. Binding of SCFR to its ligand Stem Cell Factor (PE-2008-5) induces receptor dimerization, autophosphorylation and signal transduction. SCFR is essential for the development of normal hematopoietic cells and plays an important role in the survival, proliferation and differentiation of mast cells, melanocytes and germ cells.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 12352202
- Regulatory Status For research use only.