Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
Storage InstructionsStore lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at -20°C for long-term storage. Store at 2-8°C short-term (up to 4 weeks) with an appropriate antibacterial agent. Avoid repetitive freeze/thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Alternative NamesA disintegrin and metalloproteinase with thrombospondin motifs 4; ADAMTS-4; ADAM-TS 4; ADAM-TS4; EC 18.104.22.168; Aggrecanase-1; Adamts4; ADAMTS4;
Scientific BackgroundADAMTS-4 is a glutamyl endopeptidase that cleaves aggrecan and brevican. The degradation of aggrecan, a cartilage proteoglycan, has been linked to rheumatoid arthritis, osteoarthritis, retinal diseases, Alzheimers disease and other neurodegenerative diseases.