Application DetailsWestern Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Human Histone deacetylase 2 (HDAC2) has a predicted length of 488 amino acids and MW of 55 kDa. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
TargetHistone deacetylase 2 (HD2)
SpecificityThe specificity of this antibody has been confirmed by WB against the antigen. Human; rat; mouse;
Target Host SpeciesHuman
Species ReactivityHuman, Mouse, Rat
Antibody HostRabbit
Antibody TypePolyclonal
Antibody IsotypeIgG
ConjugateUnconjugated
Immunogen DescriptionA synthetic peptide corresponding to a region (464-478 aa) from human Histone deacetylase 2.
Reconstitution InstructionsSpin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
Storage InstructionsAt least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Scientific BackgroundHistone deacetylase 2 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression, and developmental events (Ref: SWISSPROT).