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Caspase-2 (CASP-2), Rabbit Polyclonal Antibody
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US$427.00
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Catalog Number
R-1026
- Product Name Caspase-2 (CASP-2), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Caspase-2 (CASP-2) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names CASP-2; ICH-1 protease; CASP2; ICH1; NEDD2;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; rat; mouse;
- Species Reactivity Human, Mouse, Rat
- Immunogen Description A synthetic peptide (REGYAPGTEFHRCKEMSEYCSTL) corresponding to a region (417-439) from human Caspase 2
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Caspase-2 (CASP-2) Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.5-1.0 µg/mL is recommended for WB. Human Caspase 2 (Isoform ICH-1L) has a predicted length of 452 amino acids and a MW of 51 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Caspase-2 (CASP-2)
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Human; rat; mouse;
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (REGYAPGTEFHRCKEMSEYCSTL) corresponding to a region (417-439) from human Caspase 2
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions At least 12 months after purchase at 2-8°C (lyophilized formulations). After reconstitution, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names CASP-2; ICH-1 protease; CASP2; ICH1; NEDD2;
- Uniprot Number P42575
- Uniprot Number/Name P42575 (CASP2_HUMAN)
- Scientific Background Caspase 2 is a member of the cysteine-aspartic acid protease (caspase) family and acts as both a positive and negative regulator of apoptosis. Overexpression of the full length Caspase 2 (Isoform ICH-1L) in some cell types results in apoptosis whereas the overexpression of an alternative Caspase 2 (ICH-1S) splice variant suppresses apoptosis.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
