1800 605-5127
+61 (0)8 8352 7711
Integrin alpha-6 (CD49f), Rabbit Polyclonal Antibody
As low as
US$427.00
Only %1 left
Catalog Number
R-1933
- Product Name Integrin alpha-6 (CD49f), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Integrin alpha-6 (CD49f) Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Alternative Names Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD_antigen: CD49f
- Application(s) ELISA, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity Rabbit IgG polyclonal antibody for Integrin alpha 6/ITGA6 detection. Tested in WB, and direct ELISA against Human, Mouse, and Rat extracts.
- Species Reactivity Human, Mouse, Rat
- Immunogen Description E.coli-derived human Integrin alpha 6/ITGA6 (CD49f) recombinant protein (amino acids Q189-K917).
- Conjugate Unconjugated
- Purity Description Affinity Purified
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Integrin alpha-6 (CD49f) Polyclonal Antibody (Unconjugated), suitable for WB, ELISA.
- Application(s) ELISA, WB
- Application Details Western blotting (0.1-0.5 µg/mL) and direct ELISA (0.1-0.5 µg/mL). Other applications have not been tested. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Integrin alpha-6 (CD49f)
- Specificity Rabbit IgG polyclonal antibody for Integrin alpha 6/ITGA6 detection. Tested in WB, and direct ELISA against Human, Mouse, and Rat extracts.
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description E.coli-derived human Integrin alpha 6/ITGA6 (CD49f) recombinant protein (amino acids Q189-K917).
- Purity Description Affinity Purified
- Format Lyophilized
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 uL sterile-filtered, ultrapure water to obtain an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions Store lyophilized antibody at 2-8°C. After reconstitution divide into aliquots and store at -20°C for long-term storage. Store at 2-8°C short-term (up to 4 weeks). Avoid repetitive freeze/thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD_antigen: CD49f
- Uniprot Number P23229
- Uniprot Number/Name P23229 (ITA6_HUMAN)
- Scientific Background Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets (By similarity). Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion (By similarity). Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464). Source: uniprot.org. In new work published by L.Barbar [PPR83158] the authors demonstrate that CD49f is an effective marker effective marker for sorting functional human astrocytes from mixed cultures.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
