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Neuropathy target esterase, Rabbit Polyclonal Antibody
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Catalog Number
R-1135
Discontinued
- Product Name Neuropathy target esterase, Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Neuropathy target esterase Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Alternative Names Neurotoxic esterase; NTE; NTEMND; Patatin like phospholipase domain containing 6; PNPLA6; SPG39; swisscheese; sws;
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Zebrafish;
- Species Reactivity Zebra Fish
- Immunogen Description A synthetic peptide (DEDKTVRQRKNVSRDPNADFSGVSDC) corresponding to a region (1323-1348) from the C-terminus of zebrafish Neuropathy target esterase. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Conjugate Unconjugated
- Purity Description Affinity purified on antigen column
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Neuropathy target esterase Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, IHC-Paraffin-embedded.
- Application(s) IHC-Frozen, IHC-Paraffin-embedded, WB
- Application Details Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 1.0 µg/mL is recommended for WB. Zebra fish NTE has a predicted length of 1,348 residues and MW of 150 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect the protein in formalin fixed and paraffin embedded tissues. Enzymatic antigen retrieval is required. Also the recommended concentration for formalin/acetone fixed frozen tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Neuropathy target esterase
- Specificity The specificity of this antibody has been confirmed by WB and IHC against the antigen. Zebrafish;
- Target Host Species Zebra Fish
- Species Reactivity Zebra Fish
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description A synthetic peptide (DEDKTVRQRKNVSRDPNADFSGVSDC) corresponding to a region (1323-1348) from the C-terminus of zebrafish Neuropathy target esterase. To enhance the immunological response, this peptide was coupled to carrier protein BSA.
- Purity Description Affinity purified on antigen column
- Format Lyophilized with 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water to achieve an antibody concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions Aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names Neurotoxic esterase; NTE; NTEMND; Patatin like phospholipase domain containing 6; PNPLA6; SPG39; swisscheese; sws;
- Uniprot Number Q8IY17
- Uniprot Number/Name Q8IY17 (PLPL6_HUMAN)
- Scientific Background Neuropathy target esterase (NTE), also known as Patatin like phospholipase domain containing 6, is a neuronal membrane protein and a target protein for neuropathic organophosphorus (OP) compounds. The functions of NTE are not yet fully understood. NTE is suggested to have a role in neuronal development. Gene mutations in NTE have been linked with neurodegenerative diseases such motor neuron disease (MND) and amyotrophic lateral sclerosis (ALS).
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.