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C-reactive protein, Sheep Polyclonal Antibody
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Catalog Number
S-071
- Product Name C-reactive protein, Sheep Polyclonal Antibody
- Product Description Sheep anti-C-reactive protein Polyclonal Antibody (Unconjugated), suitable for WB.
- Alternative Names CRP; PTX1
- Application(s) WB
- Antibody Host Sheep
- Antibody Type Polyclonal
- Specificity It has been shown to be specific for C-reactive protein by WB. Human, other species have not yet been tested.
- Species Reactivity Human
- Immunogen Description Human recombinant C-Reactive protein
- Conjugate Unconjugated
- Purity Description Whole serum
- Regulatory Status For research use only.
Product Info
- Product Description Sheep anti-C-reactive protein Polyclonal Antibody (Unconjugated), suitable for WB.
- Application(s) WB
- Application Details WB. Extremely high titre antibody. For western blot a dilution of 1: 10,000 to 1: 100000 is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target C-reactive protein
- Specificity It has been shown to be specific for C-reactive protein by WB. Human, other species have not yet been tested.
- Target Host Species Human
- Species Reactivity Human
- Antibody Host Sheep
- Antibody Type Polyclonal
- Antibody Isotype Mixed
- Conjugate Unconjugated
- Immunogen Description Human recombinant C-Reactive protein
- Purity Description Whole serum
- Format Lyophilized with 0.01% Thimerosal
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution keep aliquots at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names CRP; PTX1
- Uniprot Number P02741
- Uniprot Number/Name P02741 (CRP_HUMAN)
- Scientific Background C-reactive protein has several roles associated with host defence such as; promoting agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. It can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. COFACTOR: Binds 2 calcium ions per subunit. C-reactive protein exists as a homopentamer. Pentaxin (or Pentraxin) have a discoid arrangement of 5 non-covalently bound subunits. There are 2 alternatively spliced isoforms. C-reactive protein is found in plasma and its concentration increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL-1 and IL-6.
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
Specifications
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General References
Lei K.-J, et al. J. Biol. Chem. 260:13377-13383(1985).
Woo P, et al. J. Biol. Chem. 260:13384-13388(1985).