SequenceA DNA sequence encoding the signal peptide and extracellular domain of human Stem Cell Factor Receptor (amino acids 1-520) was expressed in modified human 293 cells.
Purity Description>95%, as determined by SDS-PAGE, visualised by Coomassie Brilliant Blue
Purity %> 95%
FormatPurified SCFR consists of approximately 15-45% carbohydrate by weight. When reconstituted in 0.5 mL sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.
Reconstitution InstructionsReconstitute with sterile-filtered phosphate-buffered saline to a concentration of 100 µg/mL.
Storage InstructionsLyophilized products should be stored at 2 to 8°C. Following reconstitution, short-term storage at 2-8°C and longer-term storage of aliquots at -18 to -20°C is recommended. Repeated freeze thawing is not recommended.
Batch NumberPlease see item label.
Expiration Date12 months after date of receipt (unopened vial).
Scientific BackgroundStem Cell Factor Receptor (SCFR) is a member of the receptor tyrosine kinase family. Binding of SCFR to its ligand Stem Cell Factor (PE-1242-5) induces receptor dimerization, autophosphorylation and signal transduction. SCFR is essential for the development of normal hematopoietic cells and plays an important role in the survival, proliferation and differentiation of mast cells, melanocytes and germ cells.