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Tyrosine Hydroxylase (TH), Rabbit Polyclonal Antibody
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Catalog Number
R-2120
- Product Name Tyrosine Hydroxylase (TH), Rabbit Polyclonal Antibody
- Product Description Rabbit anti-Tyrosine Hydroxylase (TH), Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, ICC
- Alternative Names TH; T-H; tyrosine 3-monooxygenase; monooxygenase; oxidoreductase
- Application(s) ICC, IHC-Frozen, WB
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Specificity Human. Species cross-reactivity includes rat and mouse.
- Species Reactivity Human, Mouse, Rat
- Immunogen Description The antibody has been made against the full length recombinant human TH (524 amino acid sequence) expressed in and purified from E. Coli
- Conjugate Unconjugated
- Purity Description Affinity purified
- Regulatory Status For research use only.
Product Info
- Product Description Rabbit anti-Tyrosine Hydroxylase (TH), Polyclonal Antibody (Unconjugated), suitable for WB, IHC-Frozen, ICC
-
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- Application(s) ICC, IHC-Frozen, WB
- Application Details Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC). A dilution of 1:5,000 - 1:10,000 is recommended for WB. A dilution of 1:100 - 1:500 is recommended for IC and IH. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
- Target Tyrosine Hydroxylase (TH); Tyrosine 3-monooxyegnase
- Specificity Human. Species cross-reactivity includes rat and mouse.
- Target Host Species Human
- Species Reactivity Human, Mouse, Rat
- Antibody Host Rabbit
- Antibody Type Polyclonal
- Antibody Isotype IgG
- Conjugate Unconjugated
- Immunogen Description The antibody has been made against the full length recombinant human TH (524 amino acid sequence) expressed in and purified from E. Coli
- Purity Description Affinity purified
- Format Lyophilized from PBS buffer pH 7.2-7.6 with 0.1% trehalose, without preservatives
- Reconstitution Instructions Spin vial briefly before opening. Reconstitute with 100 µL sterile-filtered, ultrapure water to achieve a concentration of 1 mg/mL. Centrifuge to remove any insoluble material.
- Storage Instructions After reconstitution of lyophilized antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles. Store at 4°C for up to one month for short term storage and frequent use.
- Batch Number Please see item label.
- Expiration Date 12 months after date of receipt (unopened vial).
- Alternative Names TH; T-H; tyrosine 3-monooxygenase; monooxygenase; oxidoreductase
- Uniprot Number P07101
- Uniprot Number/Name P07101 (TY3H_HUMAN)
- Scientific Background Catalyzes the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa), the rate-limiting step in the biosynthesis of cathecolamines, dopamine, noradrenaline, and adrenaline. Uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-Dopa. In addition to tyrosine, is able to catalyze the hydroxylation of phenylalanine and tryptophan with lower specificity (By similarity). Positively regulates the regression of retinal hyaloid vessels during postnatal development (By similarity. (Ref: uniprot.org)
- Shipping Temperature 25°C (ambient)
- UNSPSC CODE 41116161
- Regulatory Status For research use only.
